| Email : respati@ugm.ac.id |
| Education Background : |
| Doctor, Ph.D, Osaka University, Japan, 2010. Master, M.Phil, The University of Queensland, Australia, 2006. Undergraduate, S.Si., Chemistry, FMIPA,Universitas Gadjah Mada, Indonesia, 1993 |
| Research Interest : |
| Marine Natural Products, Natural Products Membrane-Active Biomolecules, fingerprint H-NMR. Aktif meneliti tentang bahan alam terutama metabolit sekunder yang berasal dari spons laut, serta karakterisasi struktur dan uji aktivitas biologis dari senyawa tersebut. Aktif juga meneliti tentang pengembangan metode aplikasi fingerprint H-NMR berbasis metabolit sekunder dari bahan alam untuk saintifikasi dan autentifikasi obat tradisional. |
| Research Cluster/Group : |
| Bahan Alam |
| List of Publications : |
|
(1) Siswanti, D. M. J.; Gurning, K.; Haryadi, W.; Anwar, C.; Swasono, R. T. Profiling and Antibacterial Activity Assay of Secondary Metabolites from Streptomyces Isolated from Mangrove Sediment Sample. J. Multidiscip. Appl. Nat. Sci. 2025, 5 (1), 158–174. https://doi.org/10.47352/jmans.2774-3047.236. (2) Situmeang, B.; Swasono, R. T.; Raharjo, T. J. Evaluation of Phytochemical Composition, Antioxidant, Cytotoxic and in Silico Studies of Ethyl Acetate Fractions of Tristaniopsis Merguensis Leaves. Toxicol. Reports 2025, 14. https://doi.org/10.1016/j.toxrep.2025.101911. (3) Nanda, W. E.; Gurning, K.; Swasono, R. T.; Haryadi, W. Bioactive Compounds and Antimalarial Potential of Sponge Aaptos Suberitoides. J. Appl. Pharm. Sci. 2025, 15 (4), 252–261. https://doi.org/10.7324/JAPS.2025.206847. (4) Putri, R. A.; Rohman, M. S.; Swasono, R. T.; Raharjo, T. J. A Novel Synthetic Peptide Analog Enhanced Antibacterial Activity of the Frog-Derived Skin Peptide Wuchuanin-A1. J. Biomol. Struct. Dyn. 2025, 43 (1), 348–358. https://doi.org/10.1080/07391102.2023.2281633. (5) Situmeang, B.; Swasono, R. T.; Raharjo, T. J. Antioxidant, Photoprotective, and Cytotoxic Activities of Tristaniopsis Merguensis Leaf Fractions With Molecular Docking Study of Potential Fraction. Karbala Int. J. Mod. Sci. 2024, 10 (4), 406–417. https://doi.org/10.33640/2405-609X.3365. (6) Gaffar, S.; Aman, A. T.; Swasono, R. T.; Abdiani, I. M.; Yaran, Z.; Fitriani, L.; Kirana, E. Investigating the Biodiversity of Clathria Sp. Sponge Symbionts from Derawan Island, Indonesia: An Exploration of Antimicrobial, Antioxidant, and Enzyme-Producing Bacteria. Egypt. J. Aquat. Biol. Fish. 2024, 28 (2), 299–316. https://doi.org/10.21608/ejabf.2024.347842. (7) Fatmarahmi, D. C.; Susidarti, R. A.; Swasono, R. T.; Rohman, A. 1H-NMR SPECTROSCOPY AND MULTIVARIATE ANALYSIS APPLICATION ON IDENTIFYING SYNTHETIC DRUGS IN ADULTERATED PAIN RELIEVER HERBAL MEDICINE. Farmacia 2024, 72 (1), 149–155. https://doi.org/10.31925/farmacia.2024.1.15. (8) Fatmarahmi, D. C.; Susidarti, R. A.; Rohman, A.; Swasono, R. T. The Green Analytical Method of Detecting Analgesic and Antiinflammation Drugs in Pain Reliever Herbal Using Spectroscopy FTIR-ATR Combined with Multivariate Analysis. In BIO Web of Conferences; P.E.N., D., S., T., R.R., E. L., Y.V., P., B., S., D.I., J., K., T., Eds.; EDP Sciences: The Faculty of Pharmacy, Universitas Gadjah Mada, Yogyakarta, 55281, Indonesia, 2024; Vol. 135. https://doi.org/10.1051/bioconf/202413501002. (9) Hadiarti, D.; Haryadi, W.; Matsjeh, S.; Swasono, R. T.; Awaliyah, N. Profiling of α-Glucosidase Inhibitors from Ethyl Acetate Fraction of Buas-Buas (Premna Serratifolia) Leaves Using UHPLC-Q-Orbitrap HRMS and Protein–Ligand Interaction with Molecular Docking. J. Appl. Pharm. Sci. 2023, 13 (2), 89–98. https://doi.org/10.7324/JAPS.2023.130210. (10) Kusuma, W. A.; Fadli, A.; Fatriani, R.; Sofyantoro, F.; Yudha, D. S.; Lischer, K.; Nuringtyas, T. R.; Putri, W. A.; Purwestri, Y. A.; Swasono, R. T. Prediction of the Interaction between Calloselasma Rhodostoma Venom-Derived Peptides and Cancer-Associated Hub Proteins: A Computational Study. Heliyon 2023, 9 (11). https://doi.org/10.1016/j.heliyon.2023.e21149. (11) Erlista, G. P.; Ahmed, N.; Swasono, R. T.; Raharjo, S.; Raharjo, T. J. Proteome of Monocled Cobra (Naja Kaouthia) Venom and Potent Anti Breast Cancer Peptide from Trypsin Hydrolyzate of the Venom Protein. Saudi Pharm. J. 2023, 31 (6), 1115–1124. https://doi.org/10.1016/j.jsps.2023.04.001. (12) Ahmed, N.; Erlista, G. P.; Raharjo, T. J.; Swasono, R. T.; Raharjo, S. Anticancer Activity of Venom Protein Hydrolysis Fraction of Equatorial Spitting Cobra (Naja Sumatrana). Indones. J. Chem. 2023, 23 (2), 510–522. https://doi.org/10.22146/ijc.80720. (13) Pratama, B. P.; Pranoto, Y.; Swasono, R. T. The Properties of Salam Leaf Extract (Syzygium Polyanthum) with Different Solvent Ratio and Processing Time Using Ultrasonication-Assisted Extraction Method. J. Appl. Sci. Eng. 2023, 26 (4), 581–587. https://doi.org/10.6180/jase.202304_26(4).0015. (14) Habibie, A.; Raharjo, T. J.; Swasono, R. T.; Retnaningrum, E. Antibacterial Activity of Active Peptide from Marine Macroalgae Chondrus Crispus Protein Hydrolysate against Staphylococcus Aureus. Pharmacia 2023, 70 (4), 983–992. https://doi.org/10.3897/pharmacia.70.e112215. (15) Adiguna, S. P.; Panggabean, J. A.; Swasono, R. T.; Rahmawati, S. I.; Izzati, F.; Bayu, A.; Putra, M. Y.; Formisano, C.; Giuseppina, C. Evaluations of Andrographolide-Rich Fractions of Andrographis Paniculata with Enhanced Potential Antioxidant, Anticancer, Antihypertensive, and Anti-Inflammatory Activities. Plants 2023, 12 (6). https://doi.org/10.3390/plants12061220. (16) Yunitasari, N.; Raharjo, T. J.; Swasono, R. T.; Pranowo, H. D. Identification α-Amylase Inhibitors of Vernonia Amygdalina Leaves Extract Using Metabolite Profiling Combined with Molecular Docking. Indones. J. Chem. 2022, 22 (2), 526–538. https://doi.org/10.22146/ijc.71499. (17) Yunitasari, N.; Swasono, R. T.; Pranowo, H. D.; Raharjo, T. J. Phytochemical Screening and Metabolomic Approach Based on Fourier Transform Infrared (FTIR): Identification of α-Amylase Inhibitor Metabolites in Vernonia Amygdalina Leaves. J. Saudi Chem. Soc. 2022, 26 (6). https://doi.org/10.1016/j.jscs.2022.101540. (18) Ramadhan, M. F.; Astuti, E.; Swasono, R. T. Screening and Toxicity Assay of Bioactive Compounds from Ethyl Acetate Extract of Indonesian Marine Sponge Dysidia Sp. from Hoga Island. In Materials Science Forum; Trans Tech Publications Ltd: Department of Chemistry, Faculty of Mathematics and Natural Sciences, Universitas Gadjah Mada, Sekip Utara PO BOX BLS 21, Yogyakarta, 55281, Indonesia, 2022; Vol. 1061, pp 165–171. https://doi.org/10.4028/p-rg4242. (19) Pratama, B. P.; Pranoto, Y.; Swasono, R. T. The Identification of β-Ocimene Biosynthetic Pathway Through Mevalonate Acid (MVA) and 1-Deoxy-D-Xylulose 5-Phosphate (DXP) Pathways Using Crude Enzyme Extracts in Indonesian Bay Leaf/Salam Leaf (Syzygium Polyanthum). Trop. Life Sci. Res. 2022, 33 (2), 1–18. https://doi.org/10.21315/tlsr2022.33.2.1. (20) Sofyantoro, F.; Yudha, D. S.; Lischer, K.; Nuringtyas, T. R.; Putri, W. A.; Kusuma, W. A.; Purwestri, Y. A.; Swasono, R. T. Bibliometric Analysis of Literature in Snake Venom-Related Research Worldwide (1933–2022). Animals 2022, 12 (16). https://doi.org/10.3390/ani12162058. (21) Pratama, B. P.; Pranoto, Y.; Swasono, R. T. Effect of Drying Time and Temperature to the Chemical Properties and Enzymatic Activities Related to the β-Ocimene Production in Syzygium Polyanthum Leaves. Trends Sci. 2022, 19 (23). https://doi.org/10.48048/tis.2022.1526. (22) Atmawati, D. R.; Andriana, Z.; Swasono, R. T.; Raharjo, T. J. ANTIBACTERIAL PEPTIDE FROM SOLID PHASE EXTRACTION (SPE) FRACTIONATION ON TRYPSIN HYDROLYSIS OF JATROPHA (Ricinus Communis) SEED PROTEIN ACID EXTRACT. Rasayan J. Chem. 2022, 15 (2), 1288–1295. https://doi.org/10.31788/RJC.1526892. (23) Fatmarahmi, D. C.; Susidarti, R. A.; Swasono, R. T.; Rohman, A. A Development Method of FTIR Spectroscopy Coupled with Chemometrics for Detection of Synthetic Drug Adulterants of Herbal Products in Quaternary Mixture. J. Appl. Pharm. Sci. 2022, 12 (3), 191–201. https://doi.org/10.7324/JAPS.2022.120320. (24) Ahmed, N.; Raharjo, S.; Swasono, R. T.; Raharjo, T. J. THE ANTIBACTERIAL PEPTIDES (AMPs) ORIGINATED FROM TRYPTIC HYDROLYSIS OF Naja Sumatrana VENOM FRACTIONATED USING CATION EXCHANGE CHROMATOGRAPHY. Rasayan J. Chem. 2022, 15 (4), 2642–2653. https://doi.org/10.31788/RJC.2022.1548066. (25) Fatmarahmi, D. C.; Susidarti, R. A.; Swasono, R. T.; Rohman, A. Application of FTIR-ATR Spectroscopy in Combination With Multivariate Analysis to Analyze Synthetic Drugs Adulterant in Ternary Mixtures of Herbal Medicine Products. Indones. J. Pharm. 2022, 33 (1), 63–71. https://doi.org/10.22146/ijp.2609. 2021 Identification and quantification of metamizole in traditional herbal medicines using spectroscopy FTIR-ATR combined with chemometricsDC Fatmarahmi, RA Susidarti, RT Swasono, A RohmanResearch Journal of Pharmacy and Technology 14 (8), 4413-4419 2 2021 Synthesis and evaluation of chalcone derivatives as novel sunscreen agentLW Wijayanti, RT Swasono, W Lee, J Jumina Molecules 26 (9), 2698 5 2021 Antimalarial Activity of Sea Sponge Extract of Stylissa massa originating from waters of Rote IslandJ Presson, RT Swasono, S Matsjeh, MP Putri, ZA Zahra, L Pardosi Jurnal Kimia Sains dan Aplikasi 24 (4), 136-145 2021 Antibacterial Peptides from Tryptic Hydrolysate of Ricinus communis Seed Protein Fractionated Using Cation Exchange ChromatographyT Raharjo, W Utami, A Fajr, W Haryadi, R Swasono Indonesian Journal of Pharmacy, 74-85 3 2021 Sintesis Turunan Eugenol dan Uji Inhibisinya Terhadap Alfa-AmilaseV Andini, C Anwar, RT Swasono Universitas Gadjah Mada 2020 Synthesis and characterisation of a partially methylated dodecyl thiomaltotrioside derivative as a precursor of cyclodextrin analogueH Parbuntari, N Sakairi, B Purwono, RT Swasono Journal of Physics: Conference Series 1317 (1), 012032 1 2019 Synthesis, characterization and molecular docking of chloro-substituted hydroxyxanthone derivativesE Yuanita, PH Dwi, M Mustofa, SR Tri, J Syahri, J Jumina Chemistry Journal of Moldova 14 (1), 68-76 9 2019 Application of 1H-NMR based metabolite fingerprinting and chemometrics for authentication of Curcuma longa adulterated with C. heyneanaA Windarsih, A Rohman, RT Swasono Journal of Applied Research on Medicinal and Aromatic Plants 13, 100203 21 2019 Synthesis and Heme Polymerization Inhibitory Activity (HPIA) Assay of Chalcone, Flavone and Flavanone DerivativesN Suryani, S Matsjeh, RT Swasono Materials Science Forum 948, 109-114 1 2019 In vitro cytotoxic anticancer potential of bioactive fraction isolated from indonesian tidal sponge Calthropella spF Susilowati, R Swasono, T Okino, W Haryadi Asian Journal of Pharmaceutical Clinical Research 12 (1), 380-383 2 2019 Application of H-NMR metabolite fingerprinting and chemometrics for the authentication of Curcuma longa adulterated with Curcuma mangaA Windarsih, A Rohman, RT Swasono Journal of Applied Pharmaceutical Science 8 (6), 075-081 13 2018 Characterization and Photocatalytic Activity of TiO 2 (rod)-SiO 2-Polyaniline NanocompositeS Wahyuni, ES Kunarti, RT Swasono, I Kartini Indonesian Journal of Chemistry 18 (2), 321-330 10 2018 Mitochondrial ND-1 gene-specific primer polymerase chain reaction to determine mice contamination in meatballTJ Raharjo, I Nuryanti, FP Patria, RT Swasono International Food Research Journal 25 (2), 638-642 5 2018 Sintesis Nanokomposit TiO2 nanorod-SiO2-PANI sebagai Fotokatalis dan Bahan Anti-FoulingSRI WAHYUNI, I Kartini, ES Kunarti, RT Swasono Universitas Gadjah Mada 2018 Authentication of turmeric using proton-nuclear magnetic resonance spectroscopy and multivariate analysisA Windarsih, A Rohman, RT Swasono Int. J. Appl. Pharm 10, 174-180 7 2018 One-pot synthesis, antioxidant activity and toxicity evaluation of some hydroxyxanthonesE Yuanita, HD Pranowo, D Siswanta, RT Swasono, Mustofa, … CHEMISTRY & CHEMICAL TECHNOLOGY 12 (3), 290-295 7 2018 1H NMR Fingerprinting of Medicinal Herbs Contain Chemical Drug Material AllopurinolAY Puspitasari, HD Pranowo, RT Swasono, TR Nuringtyas Majalah Obat Tradisional 23 (3), 137-143 2 2018 Short Time Synthesis of Titania Nanotubes: Effect of Pre-Mixing Prior HydrothermalI Kartini, INA Jannah, FR Amalia, S Mustofa, ES Kunarti, RT Swasono Indonesian Journal of Chemistry 19 (1), 58-67 3 2018 Sintesis Senyawa Turunan Khalkon dan Flavon Berbahan Dasar Vanilin dan Uji Sitotoksik Terhadap Sel Kanker Serviks (Hela), Sel Kanker Kolon (Widr), dan Sel Kanker Payudara (T47D …E Lestari, S Matsjeh, RT Swasono BIMIPA 25 (1), 53-65 2 2018 Synthesis of 2’, 4-dihydroxy-3-methoxychalcone and 2’, 4’, 4-trihydroxy-3-methoxychalcone as a candidate anticancer against cervical (WiDr), colon (HeLa), and breast (T47D …S Matsjeh, RT Swasono, C Anwar, EN Solikhah, E Lestari AIP Conference Proceedings 1823 (1), 020048 5 2017 Study on the properties and photoactivity of TiO2 (nanorod)-SiO2 synthesized by sonication techniqueS Wahyuni, ES Kunarti, RT Swasono, I Kartini Oriental Journal of Chemistry 33 (1), 249 2 2017 Secondary metabolites and their biological activities in Indonesian soft coral of the genus LobophytumMY Putra, T Murniasih, RT Swasono, JT Wibowo, ANC Saputri, … Asian Pacific Journal of Tropical Biomedicine 6 (11), 909-913 16 2016 Phenolic content, anti-oxidant, anti-plasmodium and cytotoxic properties of the sponge Acanthella cavernosaMY Putra, T Murniasih, JT Wibowo, TA Hadi, F Untari, AC Nisa, … Asian Pacific Journal of Tropical Disease 6 (10), 811-815 2 2016 Alvina Nur AiniMY Putra, JT Wibowo, T Murniasih, RT Swasono Universitas 2019 2016 Synthesis and Antioxidant Assay of C-2-Ethoxyphenylcalix [4] resorsinareneSN Handayani, M Jumina, RT Swasono International Journal of PharmTech Research 9 (11), 103-109 3 2016 Research Article Effect of Deacetylation Degree of Chitosan as Solid Support in Lipase Immobilization by Glutaraldehyde CrosslinkTJ Raharjo, L Febrina, FA Wardoyo, RT Swasono J. Biochem. 11 (3), 127-134 8 2016 Bioassay-guided isolation of an antibacterial compound from the Indonesian soft coralMY Putra, A Saparhadi, F Karim, T Murniasih, RT Swasono Squalen Bulletin of Marine and Fisheries Postharvest and Biotechnology 11 (2 … 4 2016 Rekayasa Senyawa Trihidroksi Xanton Tersubstitusi Halogen sebagai Bahan Obat AntikankerRTS Jumina 2015 Uji Stabilitas Enzim Lipase Terimobilisasi pada Kitosan Serbuk Melalui Teknik Taut SilangFA Wardoyo, TJ Raharjo, RT Swasono PROSIDING SEMINAR NASIONAL & INTERNASIONAL 2 2015 Konversi Limbah Cangkang Kepiting Menjadi Chitosan Beads sebagai Matriks Pendukung pada Proses Imobilisasi LipaseS Primadevi, TJ Raharjo, RT Swasono Biomedika 7 (2), 34-41 2014 Membrane-active Compounds from Dinoflagellate-Structure-based Mechanism of Action of Amphidinol 3TS Respati 2010 Bioactive secondary metabolites from Australian invertebrates, Indonesian marine sponges, and an Indonesian terrestrial plantRT Swasono 2006 Novel imidazole alkaloids from Leucetta-like Indonesian spongesR Swasono, JT Blanchfield, MJ Garson 2006 Study on polyisoprenylated benzophenones from fruit of Garcinia pichrorhizaR Swasono, S Utami, S Kosela, JT Blanchfield, MJ Garson 2003 ANTIBACTERIAL PEPTIDE FROM SOLID PHASE EXTRACTION (SPE) FRACTIONATION ON TRYPSIN HYDROLYSIS OF JATROPHA (Ricinus communis) SEED PROTEIN ACID EXTRACTDR Atmawati, Z Andriana, RT Swasono, TJ Raharjo Identification α-Amylase Inhibitors of Vernonia amygdalina Leaves Extract Using Metabolite Profiling Combined with Molecular DockingN Yunitasari, TJ Raharjo, RT Swasono, HD Pranowo Indonesian Journal of Chemistry UNDERSTANDING PHYTOCHEMICAL ROLES ON α-GLUCOSIDASE INHIBITORY ACTIVITY BASED ON METABOLOMIC APPROACH OF Premna serratifolia LEAVES FROM WEST BORNEO, INDONESIAD Hadiarti, W Haryadi, S Matsjeh, RT Swasono Identifikasi Senyawa Curcumin, Bisdemethoxycurcumin dan Demethoxycurcumin Rimpang Curcuma xanthorrhiza Roxb. dan Curcuma longa L. dengan 1H NMREN Indiarto, TR Nuringtyas, YA Purwestri, RT Swasono, YB Murti Proceeding Biology Education Conference: Biology, Science, Enviromental, and |